Results
| PMID | 9102363 |
| Gene Name | PGM1 |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
| Associated genes | AMY1, AMY2, ACP1, PGM1, SOD-A, ESD, GLO1, C3, TF, PGM1 |
| Other associated phenotypes |
Endometriosis |
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Genetika. 1996 Dec;32(12):1693-9. Spitsyn, V A| Andreeva, E N| Adamian, L V| Agapova, R K| Sandoval', Kh R In a group of patients with endometriosis and in a control group of healthy women, the polymorphism of the following systems were studied: ABO and RH blood-group systems; serum proteins haptoglobin (HP), transferrin (TF), vitamin D-transporting protein (GC), protease inhibitor (PI), and the third component of the complement (C3); serum enzymes-amylase of the loci 1 and 2 (AMY1 and AMY2), pseudocholinesterase (E2), and alkaline phosphatase (PP); erythrocytic enzymes-acid phosphatase (ACP1), phosphoglucomutase (PGM1), superoxide dismutase (SOD-A), esterase D (ESD), and glyoxalase (GLO1). Statistically significant differences between the groups compared were established for five genetic systems: ABO, E2, C3, TF, and PGM1. Among patient with endometriosis, the rare alleles of the locus ESD-ESD5 and ESD7-were found, along with ESD 5-5 homozygotes. Several genetic loci can be involved in the pathogenesis of endometriosis; their products can be specifically realized due to peculiarities of biochemical reactions in the organisms of people predisposed to this pathology. Mesh Terms: ABO Blood-Group System/genetics| Adolescent| Adult| Alleles| Case-Control Studies| Complement C3/genetics| Endometriosis/*genetics| Female| *Gene Frequency| Genetic Markers| Heterozygote Detection| Humans| Isoantigens/genetics| Middle Aged| |
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